New Paragraph

A New Plaque Psoriasis
Clinical Trial to Explore
Clearer Skin

A New Plaque Psoriasis Clinical Trial to Investigate the Possibility of Clearer Skin

If you have been diagnosed with plaque psoriasis

that covers at least 10% of your body for at least six months, you may be eligible for a new clinical trial happening in your area.

If you have been diagnosed with plaque psoriasis

that covers over 10% of your body for at least six

months, you may be eligible for an exciting, new clinical trial happening in your area.

If you have been diagnosed with plaque psoriasis

that covers over 10% of your body for at least six

months, you may be eligible for an exciting, new clinical trial happening in your area.

A New Plaque Psoriasis
Clinical Trial to Explore
Clearer Skin

A New Plaque Psoriasis Clinical Trial to Investigate the Possibility of Clearer Skin

If you have been diagnosed with plaque psoriasis

that covers over 10% of your body for at least six

months, you may be eligible for an exciting, new clinical trial happening in your area.

If you have been diagnosed with plaque psoriasis

that covers at least 10% of your body for at least six

months, you may be eligible for an exciting, new clinical trial happening in your area.

If you have been diagnosed with plaque psoriasis

that covers at least 10% of your body for at least six months, you may be eligible for an exciting,
new clinical trial happening in your area.

What you need to know about the

ONWARD Psoriasis Clinical Trial

Psoriasis can be painful to live with and affect your quality of life – but doctors are searching for ways to help. People aged 18 and above who have been diagnosed with plaque psoriasis (PSO) have an opportunity to participate in a free research trial run by study-doctors who specialize in treating psoriasis. Participation will be for approximately 32 weeks for the initial portion of the trial. Additional time on an open-label extension is also possible.

Ready to Join the Trial?

See if you may qualify >>

Why join the study?

    What Are The Benefits?


  • No cost to participate or study treatment.
  • Free regular visits with study doctors who specialize in treating psoriasis (PSO).
  • Compensation and reimbursement of travel and expenses may be available if you qualify for the study.
  • Will receive either an investigative oral tablet, an approved apremilast comparator or a placebo with no active ingredients.

  • The trial is investigating whether you may see a reduction in psoriasis severity, less itchiness and perhaps clearer skin with potentially less side effects than other treatments.


What you need to know

Our research sites are currently recruiting patients to participate in the ONWARD clinical study sponsored by Alumis Inc. The study is seeking to enroll patients with plaque psoriasis to help evaluate efficacy and safety of an investigational oral TYK2 inhibitor, ESK-001. 

Psoriasis Clinical Study  Patient

Eligibility

Patients 18 years or older

You are 18 years or older, and you must weigh 88 pounds or more.

 Plaque Psoriasis Coverage

You have been diagnosed with plaque psoriasis that covers at least 10% of your body for at least six months.

 Plaque Psoriasis Coverage Hand

Your hand equals 1% of your body surface. To qualify for this study, you must have 10-hands worth of plaque psoriasis, when you add up all plaques from any part of your body.

Do you still feel you are Eligible for the study?

If yes, please read the Ineligible/ Exclusion criteria

 below carefully.

Ineligibility/ Exclusions

No Cardiovascular Disease

You do not have unstable cardiovascular disease, or cardiac hospitalization within

the last 3 months.

 Plaque Psoriasis Patient Exclusions

You have not tested Positive for Hepatitis B, C, HIV or history of known or suspected congenital or acquired immunodeficiency state that would compromise your immune system.

 Plaque Psoriasis Patient Pregnancy Exclusion

You are not pregnant or lactating or planning on getting pregnant during the study period.

Ready to join the trial?

Frequently Asked Questions

  • What is a clinical trial?

    Clinical trials are carefully designed research studies that investigate whether new drugs or treatments work to control or cure a disease, symptom, or side effect or improve quality of life.

  • Who is conducting the trial?

    Alumis Inc. is developing ESK-001 for the treatment of psoriasis and other immune-mediated inflammatory diseases.


    At Alumis we are driven to transform the lives of patients living with immune diseases using a precision approach. Learn more about Alumis here: https://www.alumis.com/

  • How long will I be in this study?

    Around 32 weeks for the initial portion of the study with the possibility of participating in the long term extension too.



  • How many people can participate in the trial?

    Only 840 eligible subjects may participate in each ONWARD plaque psoriasis clinical trial globally.

  • What is ESK-001?

    ESK-001 is a type of oral medication called a TYK2 inhibitor. It works by blocking certain proteins in your immune system which can help to reduce the severity of plaque psoriasis related signs and symptoms. ESK-001 may prove to be safer and more effective than the currently available treatments.

  • Will I be reimbursed for my travel expenses?

    Yes. This study will reimburse your reasonable travel expenses to the site closest to you.

Share by: